Platelet-rich plasma injection for symptomatic relief of disability associated with traumatic knee arthritis: a case report
Vol. 1 No. 2 (2022), Case Series and Case Reports
Vol. 1 No. 2 (2022)

Platelet-rich plasma injection for symptomatic relief of disability associated with traumatic knee arthritis: a case report

Case Series and Case Reports
https://doi.org/10.35119/myja.v1i2.30
Published 2022-12-14
Mei Leng Yap
Pain Management Clinic, Hospital Taiping, Taiping, Perak, Malaysia; Department of Anaesthesiology and Intensive Care, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia; Department of Anaesthesiology and Intensive Care, Hospital Cancelor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
Awisul Islah Ghazali
Pain Management Clinic, Hospital Taiping, Taiping, Perak, Malaysia
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Yap, M. L., & Ghazali, A. I. (2022). Platelet-rich plasma injection for symptomatic relief of disability associated with traumatic knee arthritis: a case report. Malaysian Journal of Anaesthesiology, 1(2), 133–139. https://doi.org/10.35119/myja.v1i2.30
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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Copyright (c) 2022 Mei Leng Yap, Awisul Islah Ghazali

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Keywords

knee osteoarthritis; platelet-rich plasma injection

Abstract

Multimodality is the mainstay of osteoarthritis (OA) treatment and intra-articular platelet-rich plasma (PRP) injection is gaining acceptance due to its regenerative properties and being minimally invasive. We present a young woman with Kellgren-Lawrence grade 3 post-traumatic OA in the left knee who refused surgery and opted for pain clinic follow-up. Five PRP injections in intervals of 4 to 9 months were administered in the past 2 years in addition to oral analgesia when necessary. Five ml of PRP was prepared via the double-spin open method and injected under ultrasound guidance to the left knee joint. Visual analogue scale (VAS) for pain was recorded at pre-procedure, and at 1-week and 1-month post-procedure. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was recorded at pre-procedure and 1-month post-procedure. PRP injection successfully reduced the VAS from 5 to 3 at both 1-week and 1-month post-procedure, and resulted in a WOMAC reduction of 54% with improvement in all WOMAC subscales at 1-month post-procedure. Our case showed that PRP injection demonstrated a positive effect on pain relief and physical function improvement in traumatic knee OA.

https://doi.org/10.35119/myja.v1i2.30
MyJA 30 PDF

References

Aiyong C, Huizi L, Dawei W, et al. Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine. 2020;29-30:100587. https://doi.org/10.1016/j.eclinm.2020.100587

Yeap SS, Abu Amin, SR, Baharuddin H, et al. A Malaysian Delphi consensus on managing knee osteoarthritis. BMC Musculoskelet Disord. 2021;22:514. https://doi.org/10.1186/s12891-021-04381-8

Hunter CW, Deer TR, Jones MR, et al. Consensus Guidelines on Interventional Therapies for Knee Pain (STEP Guidelines) from the American Society of Pain and Neuroscience. J Pain Res. 2022 Sep 8;15:2683-2745. https://doi.org/10.2147/JPR.S370469

Bourne RB, Chesworth BM, Davis AM, et al. Patient satisfaction after total knee arthroplasty: who is satisfied and who is not? Clin Orthop Relat Res. 2010;468(1):57-63. https://doi.org/10.1007/s11999-009-1119-9

Health Technology Assessment Section, Medical Development Division, Ministry of Health Malaysia. Platelet Rich Plasma for Treatment of Osteoarthritis (An Update). 2017. Available from: https://www.researchgate.net/publication/321936728_CPG_Management_of_Osteoarthritis_2nd_Edition https://doi.org/10.1007/s11999-009-1119-9

Ghai B, Gupta V, Jain A, et al. Effectiveness of platelet rich plasma in pain management of osteoarthritis knee: double blind, randomized comparative study. Braz J Anesthesiol. 2019;69(5):439-447. https://doi.org/10.1016/j.bjane.2019.06.005

O’Connell B, Wragg NM, Wilson SL. The use of PRP injections in the management of knee osteoarthritis. Cell Tissue Res. 2019. 376(2):143-152. https://doi.org/10.1007/s00441-019-02996-x

Dashore S, Chouhan K, Nanda S, et al. Preparation of platelet-rich plasma: national IADVL PRP taskforce recommendations. Indian Dermatol Online J. 2021. 12(1):S12-23. https://doi.org/10.4103/idoj.idoj_269_21

Huang PH, Wang CJ, Chou WY, Wang JW, Ko JY. Short-term clinical results of intra-articular PRP injections for early osteoarthritis of the knee. Int J Surg. 2017;42:117-122. http://doi.org/10.1016/j.ijsu.2017.04.067

Patel S, Dhillon MS, Aggarwal S, Marwaha N, Jain A. Treatment with platelet-rich plasma is more effective than placebo for knee osteoarthritis: a prospective, double-blind, randomized trial. Am J Sports Med. 2013 Feb;41(2):356-64. https://doi.org/10.1177/0363546512471299

Elksniņš-Finogejevs A, Vidal L, Peredistijs A. Intra-articular platelet-rich plasma vs corticosteroids in the treatment of moderate knee osteoarthritis: a single-center prospective randomized controlled study with a 1-year follow up. J Orthop Surg Res. 2020;15:257. https://doi.org/10.1186/s13018-020-01753-z

Hmamouchi I, Allali F, Tahiri L, et al. Clinically important improvement in the WOMAC and predictor factors for response to non-specific non-steroidal anti-inflammatory drugs in osteoarthritic patients: a prospective study. BMC Res Notes. 2012;5:58. https://doi.org/10.1186/1756-0500-5-58

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